Events | GWG 2018 Conference | Program

Program

Thursday, 19th of July

Pre-Meeting Genome Writers Guild Planning
Room 3-150, Cancer Cardiovascular Research Building

9:00-9:30am
GWG executive committee meeting
9:30-11:00am
GWG Society meeting

Formal Start of Conference
Memorial Hall, McNamara Building

12:00-12:05pm
Welcome
David Largaespada, PhD
12:10-12:15pm
Introduction
Jakub Tolar, MD, PhD

Session I: New Engineering Technologies

12:15-12:45pm
"Orthogonal Cas9-Cas9 Fusions Provide a Versatile Platform for Precise Genome Editing"
Scot A Wolfe, PhD (University of Massachusetts Medical School)
12:45-1:00pm
"A novel multiplexed amplicon-based NGS method to assess CRISPR off-target editing"
Selected Oral Speaker: Mark Behlke, MD, PhD
1:00-1:30pm
"Genome Engineering of Primary Cells using Base Editor Technology"
Branden Moriarity, PhD (University of Minnesota)

Session II: Cell and Gene Therapies I

1:30-2:00pm
"How to build a Registry of Regenerative Medicine Outcomes: The Carrot and the Stick"
Martin Maiers MS (Be The Match)
2:00-2:30pm
"Stem Cells in 3D: How organoids illuminate development, disease, and design"
William Hoffman MA (University of Minnesota)
2:30-3:00pm
"Nonviral synthetic polymers promote cellular and in vivo delivery of nucleic acids and genome editing"
Theresa M Reineke PhD (University of Minnesota)

Flash Talks

3:00-3:15pm
(3 x 5 mins each) from selected abstracts
Sergey Prykhozhij "Optimized knock-in of point mutations in zebrafish using CRISPR/Cas9"
Kyle Williams, PhD "New therapeutics for NF1-associated tumors and malignancies: Genetic and pharmacologic vulnerabilities"
Eric Aird "Enhancing genome editing efficiency by tethering DNA to Cas9"

Poster Session I

3:15-4:30pm
From selected abstracts

Session III: Synthetic Biology

4:30-5:00pm
"Development of a robust and scalable genetic system for Aedes aegypti population suppression"
Maciej Maselko, PhD (University of Minnesota)
5:00-5:15pm
"Dynamic Mapping of Genomic Architecture in Vivo"
Speaker selected from abstracts: Dushyant Mehra
5:15-5:45pm
"Bioengineering with synthetic cells"
Kate Adamala, PhD (University of Minnesota)

Dinner Break

5:45-7:00pm
On your own, campus area

TED Style Talks

7:00-7:15pm
"Genome writers, what are we trying to say?"
David J Odde, PhD (University of Minnesota)
7:15-7:30pm
"We Want Our Genome Story Now!"
Lynn Fellman (Fellman Studio Inc.)

Keynote Speaker

7:30-8:30pm
"Genome Editing and the DIYbio Community"
Ellen Jorgenson (Biotech Without Borders)

Friday, 20th of July

Conference Day 2
Alumni Hall, McNamara Building

Session IV: Plant Genome Engineering

8:30-9:00am
"Accelerated plant breeding using CRISPR-Cas technology"
Sergei Svitashev, PhD (DuPont)
9:00-9:15am
"CRISPR/Cas9-Mediated Mutagenesis in Soybean: from Single to Multiplexing CRISPR Targets"
Speaker selected from abstracts: Junqi Liu
9:15-9:45am
"Discovery and Application of Novel CRISPR Nucleases"
Matthew Begemann, PhD (Benson Hill Biosystems)

Session V: Regulatory Issues and Education

9:45-10:15am
"Earning Consumer Trust Through Shared Values"
Charlie Arnot (The Center for Food Integrity)
10:15-10:45am
"USDA Regulatory Approach to Plant Breeding Innovation"
Neil E Hoffman (USDA)
10:45-11:15am
"Engaging diverse voices in the era of genome editing"
Johnny Kung (Harvard Medical School)
11:15-11:45am
"This Little Piggy Went to Market; This Hornless Cow Made Milk: Gaining Regulatory Approval for Precision-Bred Food Animals"
Tammy Lee, MBA (Recombinetics)

Box lunch / Enrichment Activity

Session VI: Cell and Gene Therapies II

1:15-1:45pm
"Zinc finger nuclease-mediated ex vivo and in vivo genome editing for potential therapeutics"
Anthony Conway (Sangamo)
1:45-2:15pm
"Genetic Engineering of Human Stem Cells using Genome Editing"
Matthew Porteus, MD, PhD (Stanford University)
2:15-2:30pm
"Multiplex Human T Cell Engineering by Cas9 Base Editor Technology"
Speaker selected from abstracts: Beau Webber, PhD
2:30-3:00pm
"Exogenous Regulation of Protein Expression for Control of Gene and Cell Therapies"
Jennifer L Gori, PhD (Obsidian Therapeutics)

Session VII: Functional Genomics

3:15-3:45pm
"Genome engineering to define cancer dependencies"
William C Hahn, MD, PhD (Dana-Farber Cancer Institute)
3:45-4:15pm
"High Efficiency Genome Editing Guided by Targeted Deep Sequencing"
Shondra Pruett-Miller, PhD (St. Jude’s Children's Research Hospital)
4:15-4:30pm
"RNA-Seq identifies mutually exclusive drive insertions in PI3K-hyperactive mammary carcinomas"
Speaker selected from abstracts: Emily Pope

Flash Talks

4:30-4:45pm
(3 x 5 mins each) from selected abstracts
Zachary WareJoncas "Pioneering Targeted Mitochondrial Genome Deletions Using Zebrafish"
Nicholas Slipek "Genome-wide CRISPR screen for genetic drivers of human osteosarcoma growth and metastasis"
Dennis Webster "Homozygous RBM20R636S swine model human dilated cardiomyopathy and reveal Lou Gehrig's disease of the heart"

Poster Session II

4:45-6:00pm
From selected abstracts

Dinner Break

6:00-7:00pm
Catered Dinner

TED Style Talks

7:00-7:15pm
"Intelligent CRISPRs?"
Drena Dobbs, PhD (Iowa State University)
7:15-7:30pm
"A SLICK Way to Improve Animal Protein Production in the Tropics"
Tad Sonstegard, PhD (Recombinetics)

Keynote Speaker

7:30-8:30pm
"The impact of biology on genome enginering"
Dana Carroll, PhD (University of Utah School of Medicine)

Saturday, 21st of July

Conference Day 3
Alumni Hall, McNamara Building

Session VIII: Cell and Gene Therapies III

9:00-9:30am
"Engineering T lymphocytes to overcome tumor-dependent immunosuppression for therapeutically targeting pancreatic cancer"
Ingunn Stromness, PhD (University of Minnesota)
9:30-9:45am
"Genetic engineering of primary human NK cells for enhanced cancer immunotherapy"
Speaker selected from abstracts: Emily Pomeroy
9:45-10:15am
"Use of piggyBac transposon to manufacture Chimeric Antigen Receptor Stem Cell Memory T Cells (CAR-Tscm) with Superior Properties"
Eric Ostertag (Poseida Therapeutics)
10:15-10:30am
Coffee break

Session IX: Developmental Biology and Stem Cells

10:30-11:00am
"Increased efficiencies using homology-mediated end joining for gene targeting"
Jeffrey Essner, PhD (Iowa State University)
11:00-11:15am
"Engineering Tissue-, Cell-, and Protein-specific Staining for X-ray Microtomography"
Speaker selected from abstracts: Spencer Katz
11:15-11:45am
"From Skin to Skeletal Muscle: A Potential for Autologous Transplantation in Muscular Dystrophies"
Rita Perlingeiro, PhD (University of Minnesota)

Meeting Close

11:45am
David Largaespada

Networking and Social
Stub and Herbs
12:00pm